sensitiser - Dictionary definition and meaning for word sensitiser Definition (noun) (chemistry) a substance other than a catalyst that facilitates the start of a catalytic reaction

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WHERE SENSITIZERS ARE FOUND The OSHA Hazard Communication Standard, or HCS, defines a sensitizer as “a chemical that causes a substantial proportion of exposed people or animals to develop an allergic reaction in normal tissue after repeated exposure to the chemical” (emphasis added). Sensitizers are present environmentally and occupationally in many different industries including

In crystallography, atomic packing factor (APF), packing efficiency, or packing fraction is the fraction of volume in a crystal structure that is occupied by constituent particles. It is a dimensionless quantity and always less than unity. In atomic systems, by convention, the APF is determined by assuming that atoms are rigid spheres. The radius of the spheres is taken to be the maximum value 2019-12-12 It establishes the set of criteria to which a drug substance or drug product should conform to be considered acceptable for its intended use. "Conformance to specifications" means that the drug substance and / or drug product, when tested according to the listed analytical procedures, will meet the listed acceptance criteria. The GHS system, part of OSHA's Hazard Communication Standard (HCS), consists of nine symbols, or pictograms, providing recognition of the hazards associated with certain substances.

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A contact sensitiser is a substance that will induce an allergic response following skin contact. CONSIDERATIONS 3. The purpose of the harmonised criteria for classification of respiratory and skin sensitisers is Definition - What does Sensitizer mean? Sensitizers are chemical substances that can cause sensitization in the lungs (respiratory sensitizers) or to the skin (skin sensitizers) after exposure. Once individuals are sensitized, they can have severe reactions to further exposure, even if the exposure quantity is below the regulated occupational exposure limits. Medical definition of sensitizer: one that sensitizes: as.

9 Definition of skin and respiratory sensitisation 10 A skin sensitiser is an agent that will lead to an allergic response in susceptible 11 individuals following skin contact.

Sensitizer. Sensitizer or sensitiser may refer to: ▫ Chemical sensitizer, a chemical that causes allergic reaction in normal tissue after exposure ▫ Explosive 

Sensitizer or sensitiser may refer to: ▫ Chemical sensitizer, a chemical that causes allergic reaction in normal tissue after exposure ▫ Explosive  30 May 2017 In Europe, the CLP (Classification, Labelling and Packaging) Substance means a chemical element and its compounds in the natural state or  All hazardous chemicals (substances and mixtures) The responsibility for labelling and packaging of in packaging that meets the requirements of CLP. previously have been left blank if transport rules did not apply, which meant 23 Nov 2010 3.5 CLP rules on packaging of substances and mixtures. Respiratory sensitiser means a substance that will lead to hypersensitivity of the  Before containers of hazardous substances get to your workplace, importers and manufacturers They can also be respiratory sensitisers – meaning they can cause This is because explosives usually remain in their original packaging. Packaging of Substances and Mixtures (CLP Regulation or simply CLP) This means that labelling and packaging must respect the provisions of CLP; mutagenic or toxic to reproduction (CMR substances) and to respiratory sensitisers.

Sensitiser mean on the packaging of a substance

Animal experience or test data that the substance or mixture produces either (1) in at least one animal, effects on the cornea, iris or conjunctiva that are not expected to reverse or have not reversed; or (2) in at least 2 of 3 tested animals a positive response of corneal opacity ≥ 3 and/or iritis > 1.5, calculated as the mean scores, following grading at 24, 48, and 72 hours

Sensitiser mean on the packaging of a substance

At its fifth session (10 December 2010) the Committee of Experts adopted a set of amendments to the third revised edition of the GHS which were consolidated in document ST/SG/AC.10/38/Add.3. The Strip Packaging: It is the form of packaging in unit dosage. The advantage of strip packaging is that the shelf life of dosage is increased, and each content is protected individually.

Information and translations of sensitizer in the most comprehensive dictionary definitions resource on the web. A respiratory sensitiser is a substance which when inhaled can trigger an irreversible allergic reaction in the respiratory system. Once this sensitisation reaction has taken place, further exposure to the substance, even to the tiniest trace, may produce symptoms. 27th March, 2019. The 9 COSHH Hazard Symbols (Meanings And What They Look Like) If you are working with chemicals that are hazardous to health, or completing COSHH risk assessments, you should be aware of the symbols that are included on the packaging of substances, and what they mean. Respiratory sensitising (Sr) – Recognised respiratory sensitiser: comes from a harmonised C&L classifying the substance as Resp. Sens.
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Sensitiser mean on the packaging of a substance

You may not develop asthma immediately after working with a substance. sensitiser. In the process with HDDA it became evident that the view on how ECHA’s general approach document should be interpreted varies between member states. It also became clear that for skin sensitisers it may be difficult to provide substance-specific evidence in humans for some of the ELoC factors presented in the document.

The purpose of the harmonised criteria for classification of respiratory and skin sensitisers is Se hela listan på ilpi.com A respiratory sensitiser is a substance which, when it is breathed in, can lead to occupational asthma, which is an allergic reaction in the lungs. Once a person has developed asthma (or has been 'sensitised'), any further exposure to the substance can produce the same reaction. You may not develop asthma immediately after working with a substance.
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The noun SENSITISER has 1 sense: 1. (chemistry) a substance other than a catalyst that facilitates the start of a catalytic reaction. Familiarity information: SENSITISER used as a noun is very rare.

May produce an allergic reaction.” The aim is to protect individuals already sensitized by providing information which enables them to avoid products containing ingredients which may … 2018-09-02 Substances can be classified as skin sensitisers if there is evidence from experimental tests or in humans that the substance can lead to sensitisation by skin contact. From information in the Classification and Labelling Inventory, there are over 14 000 substances on the EU market with some indication of a skin sensitising concern.


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The first step in regulatory evaluation of substances involves the identification of their intrinsic hazards, including the potential for skin sensitization. This is, quite properly, entirely different from assessment of the risks to human health, which might arise from incorporation of substances i …

a. You can safely use it without PPE. b. (CLP stands for classification, labelling, and packaging). This Regulation Subcategories now exist for sensitisation; both skin and respiratory sensitisers may be classified as the 'health hazard' pictogram is used to indi Chemicals, CLP (Classification, Labelling and Packaging), COSHH particularly potent sensitisers, it can be even lower – although these substances are not  respiratory and skin sensitisers;; carcinogens;; reproductive toxicants; specific the type of packaging and shape of the item can change the hazard classification of Hazardous chemical means a substance, mixture or article that sa one tenth of the specific concentration limit for a substance classified as skin sensitiser or respiratory sensitiser with specific concentration limit lower than 0,1 %,  BPR (Biocidal Product Regulation), What does BPR mean? A list of chemical substances meeting criteria to qualify as a Substance of Very The Chemicals ( Hazard Information and Packaging for Supply) Regulations 2002.

In terms of skin sensitization potency, the rate to assign a substance to the next vehicle” analysis, on average in 9.3% of the cases a less severe been categorized as a strong/moderate sensitiser (Basketter et al., 2014) and was Labelling and Packaging (UN GHS/EU CLP) classification for serious eye 

Animal experience or test data that the substance or mixture produces either (1) in at least one animal, effects on the cornea, iris or conjunctiva that are not expected to reverse or have not reversed; or (2) in at least 2 of 3 tested animals a positive response of corneal opacity ≥ 3 and/or iritis > 1.5, calculated as the mean scores, following grading at 24, 48, and 72 hours 1.

How to use sensitize in a sentence. The European Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures – the CLP Regulation – came into force in all EU member states, including the UK, on 20 January 2010. The CLP Regulation: adopts in the EU the Globally Harmonised System (GHS) on the classification and labelling of chemicals; (2) Directives 67/548/EEC of 27 June 1967 and 1999/45/EC and amendments presenting requirements for testing, classification, packaging and labelling of dangerous substances and preparations, esp. Commission Directive 2001/59/EC of 6 August 2001 adapting to technical progress for the 28th time Council Directive 67/548/EEC. Sensitizer or sensitiser may refer to: . Chemical sensitizer, a chemical that causes allergic reaction in normal tissue after exposure; Explosive sensitizer, a chemical that promotes the rate of propagation of an explosive; see Chemical explosive#Sensitizer Skin Sensitizer A substance that will induce an allergic response following skin contact.